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Wednesday, September 3, 2014

Risk of autism mainly from common gene variants

August 19, 2014 - 06:22

Most of the genetic risk of autism comes from variations in common genes, rather than rare mutations.

While the direct cause of autism remains unknown, research has shown that hereditary traits are important factors. (...)

(....) Previous findings have suggested that genomes of people with autism are prone to harboring rare mutations that could be involved in causing the condition. But a major new study shows that it is the more commonly occurring gene variants, each of which individually has only a small effect, that can combine to create the biggest risk factor. (...)

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