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Wednesday, June 25, 2014

What scientists can see in your urine


Human Urine Metabolome: What scientists can see in your urine

September 5, 2013
University of Alberta





Researchers have determined the chemical composition of human urine. The study, which took more than seven years and involved a team of nearly 20 researchers, has revealed that more than 3,000 chemicals or "metabolites" can be detected in urine. The results are expected to have significant implications for medical, nutritional, drug and environmental testing. (...)

"Most medical textbooks only list 50 to 100 chemicals in urine, and most common clinical urine tests only measure six to seven compounds," said Wishart. "Expanding the list of known chemicals in urine by a factor of 30 and improving the technology so that we can detect hundreds of urine chemicals at a time could be a real game-changer for medical testing." Wishart says this study is particularly significant because it will allow a whole new generation of fast, cheap and painless medical tests to be performed using urine instead of blood or tissue biopsies. In particular, he notes that new urine-based diagnostic tests for colon cancer, prostate cancer, celiac disease, ulcerative colitis, pneumonia and organ transplant rejection are already being developed or are about to enter the marketplace, thanks in part to this work. (...)

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